Anvilus
Operator's Manual · Episode 004

Does cardio kill your gains?

What the research found, how to do it, and every source the episode cites.

The verdict

Keep your cardio.

When
you plan your training week
Then
book 2–3 cardio sessions

§ 01 · The protocol

2–3 a week
Cardio2–3 a week, 30 min
GapA few hours
OrderLift first
MeasuredLifting, with or without cardioSchumann 2022

§ 02 · Transcript

  1. The question

    Does cardio kill your gains?

  2. How it works

    Lifting flips a growth switch in your muscle. It tells the muscle to build. Cardio flips a stamina switch instead. In rats and in lab-grown cells, that switch turned the growth switch down. That's where the fear comes from.

  3. The research

    But in people, across forty-three studies, adults who added cardio built just as much muscle as those who only lifted. Their strength grew just as much, too.

  4. The protocol

    Here's how to fit it in. Aim for two or three cardio sessions a week, about thirty minutes each. Keep them a few hours away from lifting. Tired legs lift less. If you do both together, lift first, while your legs are fresh.

  5. The verdict

    So no, cardio won't kill your gains. Make it a habit, and track it with Anvilus.

§ 03 · In the sources' words

“concurrent aerobic and strength training does not interfere with the development of maximal strength and muscle hypertrophy”

“Muscle hypertrophy: 15 studies … SMD −0.01 (95% CI −0.16 to 0.18; p = 0.919). Maximal strength: 37 studies … SMD −0.06 (95% CI −0.20 to 0.09; p = 0.446)”

“possible inhibition of mechanistic target of rapamycin signalling through activation of AMP-activated protein kinase (AMPK)”

“Endurance training can lead to acute fatigue and accumulated fatigue over time (over-reaching)”

“Mean frequency: 2.9 sessions/week (untrained), 2.8 (moderately trained), 2.6 (trained). Mean duration: 37 min/session (untrained), 31 (moderately trained), 29 (trained)”

“Same-session training (≤20 min between sessions) showed an interference effect, SMD −0.31 … Sessions separated by at least 3 h did not show a significant effect”

§ 04 · Sources

  1. Schumann M, Feuerbacher JF, Sünkeler M, Freitag N, Rønnestad BR, Doma K, Lundberg TR. Compatibility of concurrent aerobic and strength training for skeletal muscle size and function: an updated systematic review and meta-analysis. Sports Med 2022;52(3):601–612 (43 studies, 1090 healthy adults, untrained or active; no funding)
  2. Petré H, Hemmingsson E, Rosdahl H, Psilander N. Development of maximal dynamic strength during concurrent resistance and endurance training in untrained, moderately trained, and trained individuals: a systematic review and meta-analysis. Sports Med 2021;51(5):991–1010 (27 studies, 750 adults; funded by the Swedish School of Sport and Health Sciences)
  3. Gao Z, Yu J. Effects of concurrent training sequence on VO2max and lower limb strength performance: a systematic review and meta-analysis. Front Physiol 2023;14:1072679 (19 RCTs, 482 adults; Chinese state research funding)
  4. Lundberg TR, Feuerbacher JF, Sünkeler M, Schumann M. The effects of concurrent aerobic and strength training on muscle fiber hypertrophy: a systematic review and meta-analysis. Sports Med 2022;52(10):2391–2403 (15 studies; no funding)
  5. Wilson JM et al. Concurrent training: a meta-analysis examining interference of aerobic and resistance exercises. J Strength Cond Res 2012;26(8):2293–2307 (21 studies; read as abstract only, contrary evidence)

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§ Keep the record

Run the protocol.
Keep the record.

Anvilus keeps your habits next to your sleep, training and nutrition, so you can see whether you actually stuck with it.